软组织恶性巨细胞瘤临床少见，容易误诊。我们自1988年9月至1997年5月手术治疗并经病理检查确诊为软组织恶性巨细胞瘤5例。为加强对本病的认识，减少误诊率，提高治疗水平，现总结如下。方法本组5例，男3例，女2例，年龄39岁～66岁，平均51岁。病程4个月至3年，病变位于左下肢1 Soft tissue giant cell tumors are rare clinically and are easily misdiagnosed. From September 1988 to May 1997, we had surgical treatment and pathological examination confirmed 5 cases of malignant giant cell tumor of soft tissue. In order to strengthen the understanding of the disease, reduce the misdiagnosis rate, and improve the treatment level, it is summarized as follows. Methods Five patients in this group, 3 males and 2 females, aged 39 to 66 years, mean 51 years old. 4 months to 3 years of disease, the lesion is located in the left lower extremity 1