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农药杀虫脒在生产和使用中均曾有中毒病例发生。本文就1984年夏秋观察到的5例施药员生产性中毒病例作一报道,供临床研究及中毒诊断标准制订时参考。 病例 例1 施药员施××,男,29岁,既往素健。于1984年7月22～24日在棉田施用杀虫脒(以下简称施药)。施药时来予特别防护,赤足,大腿以下湿透。每日工后出现嗜睡、食欲不振,乏力等症状。25日晨出现肉眼血尿,伴尿频、尿急、尿痛,一天后转镜下血尿(RBC卅～十),三天后转阴。体检:血压106/66mmHg,(基础血压120/76mmHg),脉搏75次/分,血清MAO24.82u(施药前26.28u),肝功能(ZnTT、TTT、GPT,下同)正常,心电图无异常。尿中杀虫脒及其代谢产物总量,三天工后及25日晨分别为6.141,3.473,3.268,3.390mg/l。停止施药并对症处理,逐渐恢复。
Pesticide chlordimeform in the production and use of poisoning cases have occurred. In this paper, in the summer of 1984, we observed 5 cases of drug addicts productive poisoning cases for a report for the clinical research and diagnostic criteria for the preparation of reference. Case 1 Pharmacist Shi × ×, male, 29 years old, past prime health. July 24, 1984 to 24 days in the cotton field chlordimeform (hereinafter referred to as spraying). To give special protection when spraying, barefoot, below the thigh wet. Daily drowsiness, loss of appetite, fatigue and other symptoms. 25 days morning gross hematuria, with frequent urination, urgency, dysuria, one day after the endoscopic hematuria (RBC 卅 ~ ten), three days after the negative. Physical examination: blood pressure 106/66 mmHg, basal blood pressure 120/76 mmHg, pulse 75 beats / min, serum MAO 24.82u (before administration 26.28u), liver function (ZnTT, TTT, GPT, the same below) . The total amount of chlordimeform and its metabolites in urine, three days after work and 25 morning were 6.141,3.473,3.268,3.390mg / l. Stop spraying and symptomatic treatment, and gradually recovered.