幽门螺杆菌与多种胃肠相关性疾病关系密切,可以在胃黏膜定植,产生多种有毒物质破坏胃黏膜屏障,促进胃黏膜炎症和免疫反应的发生、发展。针对其治疗虽然有国内外推荐的三联、四联疗法,但抗生素的应用造成许多不良反应,以及人群耐药性的不断增加大大降低了根治率。随着微生态学的兴起和微生态疗法的应用,为幽门螺杆菌的治疗提供了新思路。本文仅就益生菌防治幽门螺杆菌的机理作一综述。 Helicobacter pylori and a variety of gastrointestinal related diseases are closely related, can colonize the gastric mucosa, produce a variety of toxic substances to damage the gastric mucosal barrier, and promote gastric mucosal inflammation and immune response, the occurrence and development. Although its treatment has been recommended at home and abroad triple, quadruple therapy, but the application of antibiotics caused many adverse reactions, as well as the increasing population resistance greatly reduced the cure rate. With the rise of micro-ecology and the application of micro-ecological therapy, Helicobacter pylori treatment provides a new idea. This article only summarizes the mechanism of probiotics for Helicobacter pylori control.