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交换输血(下简称换血)在新生儿最大的贡献是治疗溶血性疾病、其他病原的高胆红素血症、严重贫血和多血症,在弥漫性血管内凝血和重度透明膜病的治疗中也可能有效。本文评述这两个病使用换血的合理作用及初步经验。重度透明膜病人类组织代谢依赖于氧的充分供应。红细胞因含有铁蛋白结合物(血红蛋白)有输氧作用。细胞氧的最大利用取决于数种因素:即耗氧量、肺泡换气、氧从肺泡气扩散到毛细血管床、心搏击量、血容量、血红蛋白浓度以及氧从毛细血管被动扩散到细胞等。
Exchange of blood transfusions (hereinafter referred to as transfusion) in neonatal greatest contribution to the treatment of hemolytic disease, other pathogens of hyperbilirubinemia, severe anemia and hyperlipidemia in diffuse intravascular coagulation and severe hyaline membrane disease treatment It may also be effective. This article reviews the rational use and initial experience of using transfusions in these two illnesses. Severe hyaline membrane disease in human tissue metabolism depends on the full supply of oxygen. Red blood cells contain ferritin conjugates (hemoglobin) have oxygen. The maximum utilization of cellular oxygen depends on several factors: oxygen consumption, alveolar ventilation, diffusion of oxygen from the alveolar gas to the capillary bed, cardiac stroke volume, blood volume, hemoglobin concentration, and passive diffusion of oxygen from the capillaries to the cells.