心肌缺血后长时间的冠状动脉再灌注前对缺血心肌进行反复、短暂的再缺血干预,以减轻再灌注损伤,称为缺血后处理。它是缺血心脏有效的内源性保护现象,可以减轻缺血-再灌注后心肌坏死与功能障碍,减少恶性心律失常的发生。人们对其发生机理、信号通路以及潜在的临床应用等方面已作了较多研究。现对缺血后处理的研究现状做一综述。 Myocardial ischemia for a long time after coronary reperfusion before the ischemic myocardium repeated, transient ischemic intervention to reduce reperfusion injury, known as ischemic postconditioning. It is an effective endogenous protection of ischemic heart protection phenomenon, can reduce myocardial ischemia-reperfusion after myocardial necrosis and dysfunction, reduce the incidence of malignant arrhythmias. People have made more researches on their mechanism, signal pathway and potential clinical applications. Now the research status of ischemic postconditioning is reviewed.