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目的 对巨大腹部肿瘤采用介入治疗,为肿瘤完整切除创造有利条件。方法 对12 例腹部恶性肿瘤患儿进行介入治疗,其中男7 例,女5 例。年龄2 个月~7 岁。肝母细胞瘤6 例,神经母细胞瘤3 例,肾母细胞瘤2 例,肾上腺皮质癌1 例。采用Seldinger○s 技术进行动脉插管造影,确定肿瘤主要供血动脉,进行肿瘤供血动脉超选择性插管,局部注入化疗药物,然后用碘油、明胶海绵或白芨微球栓塞肿瘤的供血动脉。结果 12 例中7 例手术切除了肿瘤,1 例剖腹探查。余下4 例通过介入治疗后,肿瘤明显缩小。12 例患儿随访追踪,至今存活10 例。结论 介入治疗既可经肿瘤供养动脉注入化疗药物,肿瘤局部化疗药物浓度高,减少全身副作用,又可阻断肿瘤供养动脉,使肿瘤缺血坏死,达到治疗目的。同时栓塞后,肿瘤包膜增厚,有利于手术中完整切除肿瘤
Objective The interventional treatment of giant abdominal tumors, to create a favorable condition for complete tumor resection. Methods 12 cases of malignant tumors of the abdomen were treated by interventional therapy, including 7 males and 5 females. Age 2 months to 7 years old. 6 hepatoblastoma, 3 neuroblastoma, 2 nephroblastoma and 1 adrenocortical carcinoma. Seldinger ○ s technique was used for arterial catheterization to determine the main artery of the tumor. The catheter was superselectively inserted into the tumor feeding artery. The chemotherapeutic drugs were locally injected. Then, the donor artery of the tumor was embolized with lipiodol, gelatin sponge, or catfish microspheres. Results Of the 12 cases, 7 had surgical resection of the tumor and 1 had exploratory laparotomy. The remaining 4 cases after interventional therapy, the tumor was significantly reduced. Twelve patients were followed up, and 10 patients survived so far. Conclusions Interventional therapy can inject chemotherapy drugs through the artery-feeding artery. High concentrations of local chemotherapy drugs can reduce the systemic side effects, and can also block the tumor-bearing artery so that tumor necrosis and necrosis can be achieved. At the same time embolization, the tumor capsule thickening, is conducive to the complete removal of the tumor surgery