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目的:调查我院烧伤病区抗菌药物的应用及细菌学情况,对细菌耐药性进行分析,对抗菌药物的合理用药进行评价。方法:利用Microsoft Excel对我院烧伤病区2007年1～12月抗菌药物的使用情况、细菌检查结果和细菌耐药性进行回顾性分析。结果:我院烧伤病区使用的抗菌药物中,β-内酰胺类药物销售金额占首位,其次是喹诺酮类和抗真菌药。按DDDs排序,列前3位的为头孢菌素类、氨基糖苷类、青霉素类,分别占32.00%,31.56%,10.42%。烧伤病区检出的134株细菌中,G~-杆菌占61.94%,其中以铜绿假单胞菌的检出率较高;G~+球菌占38.06%,以金黄色葡萄球菌为多。结论:细菌耐药性与抗菌药物的DDDs呈正相关关系。
Objective: To investigate the application and bacteriology of antibacterials in the burn area of our hospital, analyze the drug resistance of bacteria, and evaluate the rational use of antibacterials. Methods: The use of antimicrobial agents, bacterial test results and bacterial resistance in our hospital from January to December 2007 were retrospectively analyzed by Microsoft Excel. Results: Among the antibacterials used in the burn area of our hospital, the sales amount of β-lactam drugs ranked first, followed by quinolones and antifungal drugs. According to DDDs, the top three are cephalosporins, aminoglycosides and penicillins, accounting for 32.00%, 31.56% and 10.42% respectively. Of the 134 strains of bacteria found in the burn area, G ~ - bacilli accounted for 61.94%, among which the detection rate of Pseudomonas aeruginosa was higher; G ~ + bacteria accounted for 38.06%, mostly Staphylococcus aureus. Conclusion: Bacterial drug resistance is positively correlated with DDDs of antibiotics.