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原发性皮肤鼻型NK/T细胞淋巴瘤(PC-ENKTL)是一种罕见的EBV相关肿瘤,其临床病理特征目前尚未明确。作者收集亚洲多国PC-ENKTL及CD56阳性的外周T细胞淋巴瘤(PC-CD56+PTCL)60例进行回顾性分析,探讨两种淋巴瘤的临床病理特征。作者利用免疫组化T细胞受体(TCRs)、EBV原位杂交、TCR基因重排技术,将60例归类为51例PC-ENKTL(NK细胞谱系20例,T细胞谱系17例,谱系不确定14例)和9例
Primary cutaneous nasal type NK / T cell lymphoma (PC-ENKTL) is a rare EBV-associated tumor whose clinical and pathological features are not yet known. The authors collected 60 multinucleated PC-ENKTL and CD56-positive peripheral T-cell lymphoma (PC-CD56 + PTCL) in Asia for retrospective analysis of the clinical and pathological features of two kinds of lymphoma. Using immunohistochemical T-cell receptor (TCRs), EBV in situ hybridization and TCR gene rearrangement, 60 patients were classified as 51 cases of PC-ENKTL (NK cell lineage in 20 cases, T-cell lineage in 17 cases, lineage not Confirm 14 cases) and 9 cases