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放疗、手术综合治疗的优点在于手术可以切除大块肿瘤,以放射消灭潜伏灶。法国Gustave-Roassy研究所对206个经病理证实为下咽或喉鳞癌的病人,进行回顾性研究,以期明确如何应用放疗,病人按不同的治疗方案分成三组:A组95例,应用术后放疗4500拉德以上;B组59例,术后放疗,剂量不到4500拉德;C组52例,术前放疗,剂量不到4500拉德。大多数病人用~(60)Co照射。结果如下:(1)2年局部复发率A组(8%)比B组(13%)和C组(19%)低,但统计学无显著差异。可是在手术切除不彻底时,A组的局部复发率显著低于B组和C组(分别为5%、33%和28%)。(2)2年颈部复发率三组分别为14%、59%和45.5%,以A组为最低,统计学有显著差
Radiotherapy, surgery, the advantages of comprehensive treatment is that surgery can remove large tumors to eliminate latent irradiation by radiation. The Gustave-Roassy Institute of France conducted a retrospective study of 206 pathologically confirmed patients with hypopharyngeal or laryngeal squamous cell carcinoma in order to determine how radiotherapy should be applied. The patients were divided into three groups according to different treatment regimens: group A (n = 95) Post-radiotherapy more than 4500 rad; group B 59 cases, postoperative radiotherapy, dose less than 4500 rad; C group 52 cases, preoperative radiotherapy, dose less than 4500 rad. Most patients irradiated with ~ (60) Co. The results were as follows: (1) The 2-year local recurrence rate was lower in group A (8%) than in group B (13%) and group C (19%), but there was no significant difference in statistics. However, the local recurrence rate was significantly lower in group A than in groups B and C (5%, 33% and 28%, respectively) when surgical excision was incomplete. (2) The neck recurrence rates in two years were 14%, 59% and 45.5% respectively, with the lowest in group A and the statistically significant difference