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目的:观察自拟前列癃闭通方联合非那雄胺对经尿道等离子前列腺剜除术术中出血的影响,探讨中药在减少前列腺剜除术术中出血的作用。方法:选取在清远市中医院泌尿外科住院的前列腺增生症患者60例,按就诊先后顺序随机分为治疗组和对照组各30例。治疗组在术前2周口服非那雄胺5 mg/d,并服用前列癃闭通方。对照组仅在术前2周口服非那雄胺5 mg/d。两组患者均接受经尿道等离子前列腺剜除术。记录两组患者手术时间、术中冲洗量、术中出血量、切除组织出血量、术后冲洗量、术后冲洗时间。结果:治疗组患者手术时间为(52.8±16.5)min、术中冲洗量为(16.9±5.4)L、术中出血量为(78.6±17.9)m L、切除组织出血量为(2.7±2.1)m L/g、术后冲洗量为(9.4±6.3)L、术后冲洗时间为(28.6±9.7)min,而对照组相应指标分别为(71.6±17.3)min、(21.8±6.1)L、(96.4±16.7)m L、(3.6±2.3)m L/g、(16.2±5.9)L、(42.6±10.5)min,治疗组各指标均明显少于对照组(P<0.05)。结论:自拟前列癃闭通方联合非那雄胺能够减少患者经尿道等离子前列腺剜除术术中出血量。
OBJECTIVE: To observe the effect of self-made Qianliezuo Tongliao Recipe combined with finasteride on bleeding after transurethral resection of plasma prostatectomy and to explore the role of traditional Chinese medicine in reducing bleeding during prostatectomy. Methods: Sixty patients with benign prostatic hyperplasia who were hospitalized in the Department of Urology, Qingyuan Hospital of Traditional Chinese Medicine were randomly divided into treatment group (30 cases) and control group (30 cases). The treatment group was given finasteride 5 mg / d 2 weeks before the operation, and the forefront 癃 closed access. The control group received finasteride 5 mg / d only 2 weeks before surgery. Two groups of patients underwent transurethral plasma prostatectomy. The operation time, intraoperative rinse volume, intraoperative blood loss, amount of tissue resection bleeding, postoperative rinse volume and postoperative rinse time were recorded. Results: The operation time of the treatment group was (52.8 ± 16.5) min, the intraoperative flush volume was (16.9 ± 5.4) L, the intraoperative blood loss was (78.6 ± 17.9) m L and the bleeding volume was (2.7 ± 2.1) (9.4 ± 6.3) L postoperatively, and the postoperative rinse time was (28.6 ± 9.7) min, while the corresponding indexes in the control group were (71.6 ± 17.3) min and (21.8 ± 6.1) L, respectively (96.4 ± 16.7) m L, (3.6 ± 2.3) m L / g, (16.2 ± 5.9) L, and (42.6 ± 10.5) min respectively. The indexes in the treatment group were significantly less than those in the control group (P <0.05). CONCLUSIONS: The combination of finasteride and finasteride can reduce the amount of bleeding during transurethral plasma prostatectomy.