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锌是生物体内不可缺少的元素,是人体内许多重要的酶(如碳酸酐酶、碱性磷酸酶、各种蛋白酶和大多数脱氢酶)的金属成分,已证实约有80多种酶含锌。在组织呼吸中,对蛋白质的合成、红细胞膜和造血过程都有重要作用。锌对细胞的生长和对细胞的保护具有重要意义。生物体在缺乏锌时,蛋白质合成尤其是色氨酸被抑制。所以人体缺锌时可引起营养不良、侏儒症、肝脾肿大、味觉和嗅觉障碍以及性腺功能减退等综合症。通过对人发中锌含量的测定,便知体内锌含量的高低,以便决定是否采取措施来补充体内锌的含量。目前测定人发中微量锌的主要方法是原子吸收分光光度法,但由于该仪器价格较昂贵,一般实验室不能开展此项实验。而用5—Br—PADAP在TritonX-100非离子表面活性剂存在下
Zinc is an indispensable element in the body and is a metal component of many important enzymes in the human body, such as carbonic anhydrase, alkaline phosphatase, various proteases and most dehydrogenases. It has been confirmed that about 80 enzymes Zinc. In tissue respiration, the synthesis of proteins, erythrocyte membrane and hematopoietic processes have an important role. Zinc is important for cell growth and cell protection. In the absence of zinc in organisms, protein synthesis, especially tryptophan, is inhibited. Therefore, zinc deficiency can cause malnutrition, dwarfism, hepatosplenomegaly, taste and smell disorders and hypogonadism and other syndromes. Through the determination of human hair zinc content, we know the level of zinc in vivo in order to decide whether to take measures to supplement the body’s zinc content. At present, the main method for the determination of trace zinc in human hair is atomic absorption spectrophotometry. However, due to the relatively expensive equipment, the general laboratory can not carry out this experiment. While using 5-Br-PADAP in the presence of Triton X-100 non-ionic surfactant