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原发性IgA肾病(IgA nephropathy,IgAN)是经病理确诊的最常见的肾小球疾病,其预估的年发生率至少为2.5/10万[1]。实际上IgAN发展到得到临床关注的只是这一庞大患者群的冰山一角。尸检和肾移植时即刻肾活检显示无临床症状的IgAN的发病率可能高达1.6%[2,3],绝大部分原发性IgAN并未得到肾活检证实和临床关注。在对于仅有尿检异常的患者的研究中,通常孤立的镜下血尿,经肾活检明确IgAN,
Primary IgA nephropathy (IgA) is the most common pathological diagnosis of glomerular disease, the estimated annual incidence of at least 2.5 / 10 million [1]. In fact, IgAN has only progressed to the tip of the iceberg that has received clinical attention. Autopsy and renal biopsy at the time of kidney transplantation showed no clinical symptoms of IgAN may be as high as 1.6% [2,3], the vast majority of primary IgAN did not receive renal biopsy confirmed and clinical attention. In studies of patients with only urinalysis abnormalities, usually isolated microscopic hematuria, confirmed by renal biopsy IgAN,