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目的探讨阿托伐他汀(立普妥)治疗脑梗死患者颈动脉粥样硬化斑块的效果。方法选择2008年11月~2014年11月我院收治的脑梗死患者150例,对照组给予常规治疗,治疗组在此基础上加用立普妥治疗,治疗周期为4周。结果所有患者都完成治疗,两组治疗后颈动脉内膜中层厚度和斑块面积都低于治疗前(P<0.05),同时治疗后治疗组的颈动脉内膜中层厚度和斑块面积低于对照组(P<0.05)。结论立普妥治疗脑梗死患者能有效改善颈动脉粥样硬化斑块状况。
Objective To investigate the effect of atorvastatin (Lipitor) on carotid atherosclerotic plaque in patients with cerebral infarction. Methods 150 patients with cerebral infarction admitted to our hospital from November 2008 to November 2014 were enrolled. Patients in the control group were given routine treatment. The treatment group was treated with Lipitor on the basis of this treatment, and the treatment period was 4 weeks. Results All patients completed the treatment. The mean carotid intima-media thickness and plaque area in both groups were lower than those before treatment (P <0.05), meanwhile, carotid intima-media thickness and plaque area in the treatment group were lower than Control group (P <0.05). Conclusion Lipitor treatment of patients with cerebral infarction can effectively improve the carotid atherosclerotic plaque status.