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空间生物反应器是人类利用空间资源进行空间生物学与空间生物技术研究的重要硬件设备,其应用为空间生命科学研究提供了必要的生物材料,如细胞、组织和微生物等。本文针对空间生物反应器对空间生物学和空间生物技术的重要作用,综述了空间生物反应器的研制发展历程和现状,并对灌流式中的旋转壁式生物反应器、细胞培养单元反应器、单环路细胞培养反应器、微型连续培养反应器和非灌流式中的多层逆流细胞培养反应器、新型膜生物反应器等空间生物反应器的主体结构和工作原理做了介绍。最后,对空间生物反应器的发展趋势进行了分析和展望。
The space bioreactor is an important hardware device for human use of space resources for space biology and space biotechnology research. Its application provides the necessary biological materials for space life science research, such as cells, tissues and microorganisms. In this paper, space bioreactor for space biology and space biology and biotechnology important role, reviewed the development of space bioreactor development and status quo, and perfusion in the rotating wall bioreactor, cell culture unit reactor, Single loop cell culture reactor, mini continuous culture reactor and non-perfusion multi-layer countercurrent cell culture reactor, a new type of membrane bioreactor space bioreactor the main structure and working principle are introduced. Finally, the development trend of space bioreactor is analyzed and forecast.