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目的分析婴幼儿EB病毒感染的临床特点,提高临床诊疗水平。方法对聚合酶链反应技术(PCR)测定的EBV-DNA阳性的71例EB病毒感染患儿的临床特征进行回顾性分析。结果 EB病毒感染的主要症状有发热98.6%、咽峡炎70.4%、淋巴结肿大19.7%、肝脾肿大8.5%、皮疹12.7%、咳嗽63.4%,其他还包括呕吐、腹泻、眼睑水肿、惊厥等,EB病毒感染的相关疾病以呼吸系统最常见,其次是循环系统、血液系统等。结论婴幼儿EB病毒感染临床表现复杂多样,PCR技术测定EBV-DNA有助于早期诊断。
Objective To analyze the clinical features of EB virus infection in infants and young children and improve the clinical diagnosis and treatment. Methods The clinical features of 71 Epstein-Barr virus positive EBV-DNA-positive children with Epstein-Barr virus (EBV-DNA) infection detected by polymerase chain reaction (PCR) were retrospectively analyzed. Results The main symptoms of EB virus infection were fever 98.6%, angina 70.4%, lymph node enlargement 19.7%, hepatosplenomegaly 8.5%, rash 12.7% and cough 63.4%. Others included vomiting, diarrhea, eyelid edema and convulsion Etc., Epstein-Barr virus infection-related diseases to the respiratory system is the most common, followed by the circulatory system, the blood system. Conclusion The clinical manifestations of Epstein-Barr virus infection in infants and young children are complex and diverse. The detection of Epstein-Barr virus DNA by PCR is helpful for the early diagnosis.