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目的：研究膳食中钙因素与心肌损伤的关系。方法：用７０只Ｗｉｓｔａｒ大鼠，按体重和性别均匀分层分为低钙膳食组（ＬＣＧｒｏｕｐ含钙３００ｍｇ／ｋｇ）、补碳酸钙组（补钙３００、６００、１０００、２０００、４０００ｍｇ／ｋｇ），常规饲料组（Ｓｔｏｃｋｇｒｏｕｐ，含钙７８００ｍｇ／ｋｇ）等７组。饲养５６天。结果：低钙膳食大鼠血清Ｃａ水平仅及常规饲料组一半，体重增长迟缓，血清ＧＯＴ，ＣＫ－ＭＢ活性均高于常规饲料组，ＬＤＨ，ＨＢＤＨ活性均低于常规饲料组，同时心肌和血清过氧化脂质水平明显高于常规饲料组，ＳＯＤ水平低于常规饲料组，均有显著差异。补钙后血Ｃａ水平随补Ｃａ量逐渐升高，呈明显的量效关系。血清酶活性明显改善，均趋向ｓｔｏｃｋ组。补Ｃａ各组可使过氧化脂质水平下降；ＳＯＤ活性升高。综合分析，补Ｃａ６００ｍｇ／ｋｇ以上组与ＬＣ组比有显著差异。结论：膳食低钙时补钙对心肌起保护作用
Objective: To study the relationship between dietary calcium and myocardial injury. Methods: 70 Wistar rats were divided into low calcium diet group (LCGroup containing 300mg / kg calcium), calcium carbonate group (300,600,1000,2000,4000mg / kg) , Conventional feed group (Stockgroup, calcium 7800mg / kg) and other 7 groups. Feeding 56 days. Results: Serum Ca levels in low-calcium diet rats were only half that of the normal diet group, with slow growth of body weight, serum GOT, CK-MB activity were higher than the conventional diet group, LDH, HBDH activity were lower than the conventional diet group, while myocardial and serum Lipid peroxidation levels were significantly higher than the conventional diet group, SOD levels were lower than the conventional diet group, were significantly different. After calcium supplement, blood Ca level gradually increased with Ca supplement, showing a significant dose-response relationship. Serum enzyme activity improved significantly, both toward the stock group. Supplementation Ca each group can reduce lipid peroxidation levels; SOD activity increased. Comprehensive analysis, make up Ca600mg / kg more than the LC group compared with significant differences. Conclusion: Calcium supplementation can protect the myocardium from dietary low calcium