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目的探讨原发性肝癌患者手术后发生感染的相关因素。方法选取新疆医科大学附属肿瘤医院2012年2月至2015年1月收治的108例行肝切除术的原发性肝癌患者,根据术后是否发生感染分为感染组和非感染组。分析可疑危险因素与肝切除术后发生感染的关系。结果 108例患者中,20例发生术后感染,占18.52%。感染组和非感染组在糖尿病史、病灶、血管癌栓、手术时间、术中出血量、术中输血量、引流管放置时间、术前使用抗菌药物、营养不良和血清清蛋白方面比较差异有统计学意义(P<0.05),Logistic回归分析显示,合并有糖尿病、病灶多发、血管癌栓、手术时间、引流管放置时间、术前使用抗菌药物、营养不良和血清清蛋白为原发性肝癌患者手术后发生感染的独立影响因素(P<0.05)。结论合并有糖尿病、病灶多发、血管癌栓、手术时间、引流管放置时间和血清清蛋白为原发性肝癌患者手术后发生感染的独立危险因素。
Objective To investigate the related factors of postoperative infection in patients with primary liver cancer. Methods A total of 108 primary hepatocellular carcinoma patients who underwent hepatectomy from February 2012 to January 2015 in Cancer Hospital of Xinjiang Medical University were divided into infected group and non-infected group according to whether they were infected or not. To analyze the relationship between suspicious risk factors and infection after liver resection. Results Among 108 patients, 20 cases had postoperative infection, accounting for 18.52%. There were significant differences in the history of diabetes mellitus, lesion, vascular thrombosis, operation time, intraoperative blood loss, intraoperative blood transfusion, drainage tube placement time, preoperative use of antimicrobial drugs, malnutrition and serum albumin in infected and noninfected groups Statistical analysis (P <0.05) Logistic regression analysis showed that patients with primary liver cancer were complicated with diabetes mellitus, multiple lesions, vascular thrombosis, operation time, drainage tube placement time, preoperative use of antimicrobial drugs, malnutrition and serum albumin The independent influencing factors of infection occurred in patients after operation (P <0.05). Conclusions There is an independent risk factor for infection after operation in patients with primary liver cancer complicated with diabetes mellitus, multiple lesions, vascular thrombosis, operation time, drainage tube placement time and serum albumin.