论文部分内容阅读
氟比洛芬(flurbiprofen)是一种非甾体抗炎药物,临床用于治疗膝关节炎、风湿性关节炎、疼痛和相关肌骨骼痛。本研究的目的是评价氟比洛芬与另一个非甾体抗炎药双氯芬酸治疗膝关节炎时的疗效、耐受性和药物的安全性。对74例患典型膝关节炎已至少2个月的患者进行随机双盲试验。患者主要为白人和妇女,年龄35～75岁。氟比洛芬组和双氯芬酸组患关节炎分别为70和77个月。给予氟比洛芬或双氯芬酸50mg,每日3次,连续6周。未伍用阿司匹林、皮质激素类药物及其它非甾体抗炎药或抗凝剂。某些患者在治疗前后曾服用过一段时间的
Flurbiprofen is a non-steroidal anti-inflammatory drug used clinically for the treatment of knee arthritis, rheumatoid arthritis, pain and related skeletalgia. The purpose of this study was to evaluate the efficacy, tolerability and drug safety of flurbiprofen in combination with diclofenac, another non-steroidal anti-inflammatory drug, for the treatment of knee osteoarthritis. A randomized, double-blind trial of 74 patients with typical knee arthritis for at least 2 months was performed. Patients are mainly white and women, aged 35 to 75 years old. Arthritis in the flurbiprofen group and diclofenac group were 70 and 77 months, respectively. Give flurbiprofen or diclofenac 50mg 3 times daily for 6 weeks. No aspirin, corticosteroids and other non-steroidal anti-inflammatory drugs or anticoagulants. Some patients have taken some time before and after treatment