目的探讨腹腔镜手术及术后及时加用克罗米芬（ＣＣ）和人绒毛膜促性腺素（ＨＣＧ）促排卵治疗对单一用ＣＣ治疗无效的ＰＣＯＳ患者的疗效。方法将２５例用ＣＣ治疗无效的ＰＣＯ患者采用电视腹腔镜下卵巢多点穿刺、内凝法及术后加用ＣＣ＋ＨＣＧ促排卵治疗。结果２５例患者中共１８例妊娠，妊娠率７２％。结论腹腔镜穿刺、内凝卵巢辅以促排卵治疗对单一用克罗米芬治疗无效的ＰＣＯＳ病人有较好疗效。 Objective To investigate the curative effect of laparoscopic surgery and timely administration of clomiphene citrate (C  C) and human chorionic gonadotropin (HCG) on ovulation induction in patients with PCOS who were treated with C  C alone. Methods Twenty-five patients with PCO who were ineffective with CC were treated with laparoscopic ovarian puncture, internal coagulation and postoperative C  C + HCG ovulation induction therapy. Results A total of 18 cases of pregnancy in 25 patients, the pregnancy rate was 72%. Conclusions Laparoscopic puncture and internal coagulation ovary supplemented with ovulation induction treatment have a good curative effect on single invalid PCOS patients treated with clomiphene.