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目的观察高压氧(hyperbaric oxygen,HBO)对深度烧伤植皮治疗创面愈合的影响进行回顾性分析。方法31例烧伤患者分为2组,入院后1～7天,采用一次性切(削)痂植皮,常规处理方法。氧疗组采用切痂或药物脱痂后肉芽创面1次植皮常规处理方法后,即开始高压氧治疗。结果治疗组术后无植皮创面感染,对照组有2例出现植皮创面感染。治疗组愈合时间7～35天,平均(11.5±2.5)天;对照组为12～62天,平均(21.4±5.7)天,两组比较差异有显著性意义(P<0105)。结论对于深度烧伤创面,根据患者的全身情况应尽早切(削)痂植皮,同时最好在24小时内配合HBO治疗,有利于创面的愈合,缩短愈合时间,减少瘢痕生成,从而提高烧伤患者治愈率及生活质量。
Objective To investigate the effect of hyperbaric oxygen (HBO) on wound healing after deep burn skin grafting. Methods 31 cases of burn patients were divided into two groups, 1 to 7 days after admission, using a one-time cut (cut) crust grafting, conventional treatment. Oxygen therapy group after escharectomy or drug scab wound granulation wounds after a routine skin grafting treatment, the hyperbaric oxygen therapy began. Results There were no skin graft wounds in the treatment group and two skin grafting wounds in the control group. The healing time of the treatment group was 7 to 35 days (mean 11.5 ± 2.5 days). The control group was 12 to 62 days (mean 21.4 ± 5.7 days). There was significant difference between the two groups (P <0.05). Conclusion For deep burn wounds, scab skin graft should be cut as soon as possible according to the general condition of the patient. In the meantime, it is best to cooperate with HBO within 24 hours, which is beneficial to wound healing, shortening the healing time and reducing scar formation, thus improving the healing of burn patients Rate and quality of life.