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目的观察异甘草酸镁治疗慢性乙型肝炎(CHB)的临床疗效。方法将80例CHB患者随机分为治疗组(40例)和对照组(40例)。治疗组给予异甘草酸镁100mg加入10%葡萄糖250ml中静脉滴注,1次?d,4周为1个疗程。结果异甘草酸镁可明显改善临床症状和肝功能,治疗组临床疗效显著优于对照组(P<0.05),且无明显不良反应。结论异甘草酸镁是治疗CHB有效药物,无明显不良反应,有临床推广应用价值。
Objective To observe the clinical efficacy of magnesium isoglycyrrhizinate in the treatment of chronic hepatitis B (CHB). Methods Eighty CHB patients were randomly divided into treatment group (40 cases) and control group (40 cases). The treatment group was given magnesium isoglycyrrhizinate 100mg 10% glucose 250ml intravenous drip, 1 d, 4 weeks for a course of treatment. The results of magnesium glycyrrhizinate can significantly improve the clinical symptoms and liver function, the clinical efficacy of the treatment group was significantly better than the control group (P <0.05), and no significant adverse reactions. Conclusion Magnesium isoglycyrrhizinate is an effective drug for the treatment of CHB, no obvious adverse reactions, clinical application value.