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目的 :研究抗心磷脂抗体 (ACA)与脑血管病的关系 ,为脑卒中的预测提供临床依据。方法 :采用前瞻性研究方法 ,对 91例脑梗死 (CI)、4 2例脑出血 (CH)患者及 30例健康者血清中的抗心磷脂抗体 (ACA)进行检测。结果 :CI及 CH组 ACA总阳性率、Ig G型 ACA阳性率均显著高于对照组。ACA阳性卒中容易复发 ,病灶常为多个。ACA在脑卒中发病一周内阳性率最高 ,且抗体分型以 Ig G型为主。结论 :ACA是 CI及 CH的危险因素 ,对脑卒中的预测有一定意义
Objective: To study the relationship between anticardiolipin antibodies (ACA) and cerebrovascular disease and to provide a clinical basis for the prediction of stroke. Methods: A prospective study was conducted to detect the anticardiolipin antibody (ACA) in serum of 91 patients with cerebral infarction (CI), 42 patients with cerebral hemorrhage (CH) and 30 healthy controls. Results: The positive rate of ACA and IgA positive rate of ACA in CI and CH groups were significantly higher than those in control group. ACA-positive stroke prone to recurrence, often multiple lesions. The highest positive rate of ACA in stroke within one week, and antibody type to Ig G type. Conclusion: ACA is a risk factor for CI and CH, which has some significance for the prediction of stroke