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我院应用激素并噻替派治疗肾病综合征,出现2例严重粒细胞缺乏症,而肾病综合征得到缓解,现报告如下: 例1女,48岁,农民,住院号290072。因反复颜面及双下肢浮肿、蛋白尿1年于1985年9月30日入院,颜面及双下肢明显凹陷性浮肿,血压16/10.66kPa,心肺无异常,肝脾未触及,Hb119g/L,WBC10.8×10~9/L,N0.74,L0.24,E0.02.尿常规:蛋白+++。尿蛋白定量5.8 g/d,尿圆盘电泳4～8万分子量区带出现蛋白,尿FDP5μg/ml.Ccr38.5ml/min,BUN8.04mmol/L,Scr104.9μmol/L.血清C_3(一),胆固醇7.07mmol/L,总蛋白33g/L,蛋白电泳:白蛋白28.6%,球蛋白α_17.3%,α_223.8%,β21.3%,γ19%.血沉42mm
Hormone therapy in our hospital and thiophene treatment of nephrotic syndrome, two cases of severe agranulocytosis, nephrotic syndrome and neutropenia were alleviated, are as follows: 1 female, 48 years old, hospitalization number 290072. Due to repeated facial and double lower extremity edema, proteinuria was admitted to hospital on September 30, 1985, the facial and bilateral lower extremities were significantly depressed edema, blood pressure 16 / 10.66kPa, no abnormal heart and lung, liver and spleen not touched, Hb119g / L, WBC10 .8 × 10 ~ 9 / L, N0.74, L0.24, E0.02. Urine routine: protein +++. Proteinuria, urinary FDP5μg / ml.Ccr38.5ml / min, BUN8.04mmol / L, Scr104.9μmol / L. Serum C_3 (a) , Cholesterol 7.07mmol / L, total protein 33g / L, protein electrophoresis: albumin 28.6%, globulin α-17.3%, α_223.8%, β21.3%, γ19%