该研究检验是否免疫细胞参与Dahl盐敏感大鼠高血压和肾脏疾病的发生发展及其机制。当饮食中氯化钠摄入量从0.4%增加至4.0%时,浸润至肾脏的T淋巴细胞数目显著增加[从(8.8±1.2)×105增加至(14.4±2.0)×105个细胞/2侧肾脏],动脉血压升高[从(131±2)升至(165±6)mm Hg],尿白蛋白 The study examined whether immune cells are involved in the pathogenesis of hypertension and renal disease in Dahl-sensitive rats and their mechanisms. When the dietary intake of sodium chloride increased from 0.4% to 4.0%, the number of T lymphocytes infiltrating into the kidney increased significantly from (8.8 ± 1.2) × 105 to (14.4 ± 2.0) × 105 cells / 2 Side kidney], elevated arterial pressure (from 131 ± 2 to 165 ± 6 mm Hg), urinary albumin