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目的观察头孢哌酮/舒巴坦与头孢哌酮治疗医院获得性肺炎疗效比较。方法将60例医院获得性肺炎患者随机分为两组,治疗组30例采用头孢哌酮/舒巴坦治疗,对照组30例采用头孢哌酮治疗。比较两组治疗前后患者体温,呼吸道症状,肺部啰音,血常规,X线,细菌学检查等改善情况及治疗中出现的不良反应。结果治疗组总有效率93.3%,对照组总有效率83.3%,差异有统计学意义(χ2=5.06,P<0.05),治疗过程无明显不良反应。结论头孢哌酮/舒巴坦治疗医院获得性肺炎临床疗效优于头孢哌酮。
Objective To compare the efficacy of cefoperazone / sulbactam and cefoperazone in the treatment of hospital-acquired pneumonia. Methods Sixty patients with hospital acquired pneumonia were randomly divided into two groups. The treatment group was treated with cefoperazone / sulbactam and the control group with cefoperazone. The improvement of body temperature, respiratory symptoms, pulmonary rales, blood routine, X-ray and bacteriological examination were compared between the two groups before and after treatment and the adverse reactions occurred in the treatment. Results The total effective rate was 93.3% in the treatment group and 83.3% in the control group. The difference was statistically significant (χ2 = 5.06, P <0.05). There was no obvious adverse reaction during the treatment. Conclusion Cefoperazone / sulbactam is superior to cefoperazone in the treatment of hospital-acquired pneumonia.