报道了6-甲氧基-1,2,3,9-四氢-4H-咔唑-4-酮肟(3b)的一锅合成法,将Fischer吲哚合成与肟化两步反应并为一步,可简化操作,提高收率.反应可以在弱碱性且温度温和的条件下一锅合成,是由于肟化使Fischer吲哚环合变得容易,羰基与肟基在互变异构方向上的差别是影响环合反应的关键因素. A one-pot synthesis of 6-methoxy-1,2,3,9-tetrahydro-4H-carbazol-4-one oxime (3b) was reported. The Fischer indole synthesis and oximation two- The one-step procedure simplifies the process and improves the yield.The reaction can be performed in one-pot at mildly basic and mild conditions due to the oximation of the Fischer indole ring, the carbonyl group and the oxime group in the tautomerism The difference is the key factor affecting the cyclization reaction.