目的探讨急性肢体动脉闭塞的血管内介入治疗方法和疗效。方法采用介入导管尿激酶溶栓治疗急性肢体动脉闭塞患者42例,发病时间10～66h。结果 42例病人经导管溶栓治疗后闭塞血管均再通,其有效率为100%,临床症状消失。结论介入导管溶栓术可作为急性肢体动脉闭塞的基础疗法。它的溶栓成功率高,出血并发症很少。 Objective To investigate the method and effect of endovascular interventional treatment of acute limb arterial occlusion. Methods Thirty-two cases of acute extremity arterial occlusion were treated by interventional catheter urokinase thrombolysis with the onset time ranging from 10 to 66 hours. Results 42 cases of patients after catheter thrombolysis occlusion vessels were reopened, the effective rate was 100%, the clinical symptoms disappeared. Conclusion Interventional catheter thrombolysis can be used as the basic therapy for acute limb artery occlusion. It has a high success rate of thrombolysis, bleeding complications rarely.