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目的使用黄芪联合高效抗逆转录病毒治疗(HAART)治疗艾滋病,与常规HAART治疗对比,观察其降低副作用及治疗艾滋病效果。方法研究组收集22例艾滋病患者黄芪联合HAART治疗24周,对照组收集20例艾滋病患者常规HAART治疗24周。观察两组治疗后药物副作用及抗艾滋病疗效对比情况。结果治疗24周后研究组在消化道反应、外周神经炎、皮疹、皮肤瘙痒及肝功能损害方面药物副作用较对照组发生少,有统计学意义。治疗后研究组CD4+细胞数为256.80±102.58,对照组为240.26±96.62,差异有统计学意义。结论黄芪联合HAART治疗可以减少HAART治疗副作用,增强患者免疫力,加速HAART治疗后的免疫重建。
Objective To compare the efficacy and safety of Astragalus root combined with highly active antiretroviral therapy (HAART) in the treatment of AIDS with routine HAART and to observe its effect of reducing side effects and treating AIDS. Methods The research group collected 22 cases of AIDS patients with astragalus combined HAART for 24 weeks, control group collected 20 cases of AIDS patients with conventional HAART for 24 weeks. To observe the side effects of drugs after treatment and anti-AIDS efficacy comparison. Results After 24 weeks of treatment, the side effects of the drugs in the gastrointestinal tract reaction, peripheral neuritis, skin rash, pruritus and liver damage were fewer than those in the control group, with statistical significance. After treatment, the number of CD4 + cells in the study group was 256.80 ± 102.58 and in the control group was 240.26 ± 96.62, the difference was statistically significant. Conclusion Astragalus combined with HAART treatment can reduce side effects of HAART treatment, enhance patient immunity and accelerate the immune reconstitution after HAART treatment.