球红霉素是我国首先创制成功的抗真菌抗菌素,它对白色念珠菌及新型隐球菌等深部真菌有较好的抗菌作用,故适用于对深部真菌病的治疗。我院于1975—1977年曾应用福建省微生物研究所和福州抗菌素厂生产的球红霉素治疗4例内脏白色念珠菌病均获得显著效果。现报导如下以供参考。病例介绍周××,男性,26岁,住院号26347。患者以弛张型发热、咳嗽和胸痛40天转来本院。于发病第9天出现巩膜黄染、心包炎和胸腔积液,在外院曾用青、链、卡那、新青等抗菌素及肾上腺皮质激素等治疗,而症状始终未能控制,病情日益加重,故转来本院。入院时体检,患者一般情况差,消瘦贫血貌,口咽部和舌部有白色斑点,两肺下部有湿性罗音,心脏听诊除心率较快外无异常发现,腹软,肝脾不肿大,皮肤 Erythromycin is the first successful antifungal antibiotic in China. It has good antibacterial activity against deep fungi such as Candida albicans and Cryptococcus neoformans, so it is suitable for the treatment of deep fungal diseases. Our hospital from 1975 to 1977 had applied Fujian Institute of Microbiology and Fuzhou antibacterial plant production of globoside in the treatment of 4 cases of visceral candidiasis have achieved significant results. Now reported as follows for reference. Case description Week × ×, male, 26 years old, hospital number 26347. Patients are referred to our hospital for 40 days as relax fever, cough and chest pain. Sclera yellow dye, pericarditis and pleural effusion appeared on the 9th day of onset. Antibiotics and adrenocortical hormones such as green, chain, kaina and new youth were treated outside the hospital. However, the symptoms were not controlled and their condition was getting worse. So turn to our hospital. Physical examination on admission, the patient generally poor, emaciated anemia, oropharynx and tongue with white spots, lower lungs have wet rales, heart auscultation in addition to faster heart rate exception was found, abdominal soft, hepatosplenomello not swollen ,skin