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为探讨血吸虫病大肠癌切除术后肝转移的化学治疗。对 40例血吸虫病大肠癌肝转移患者行化学栓塞治疗 ,通过肝动脉的选择性血管造影术识别转移的营养血管 ,向该血管注射化学乳剂 (由 10 0 m g 5 - Fu,10 mg MMC和 10 ml超液化碘化罂粟油 ) ,然后用止血棉塞栓塞 ,直到血液不流动为止。结果显示 ,从第一次化学栓塞起 ,总的中数生存期为 10个月。当肝硬化程度按 Child- Pugh分级时 ,A级与 B级的中数生存期较有肝外转移者高 (P<0 .0 2 ) ,分别为 14个月和 3个月 ;血管多的转移癌中数生存期较血管少的转移癌的中数生存期高 ,有显著差异 (P<0 .0 1) ;最常见的副作用是短暂的发热、腹痛和疲劳 ;在化疗过程中有 3人死亡。血吸虫病大肠癌肝转移全身化疗的疗效不佳 ,且副作用较多 ,选择性化学栓塞治疗不仅疗效好 ,且副作用少 ,可预防肝功能衰竭 ,延长生存期
To investigate the treatment of schistosomiasis after colorectal cancer resection of liver metastases. Forty cases of schistosomiasis patients with liver metastases from colorectal cancer underwent chemoembolization, and the vessels were identified by selective angiography of the hepatic artery. The chemical emulsion was injected into the vessels (composed of 10 mg 5 - Fu, 10 mg MMC and 10 ml liquefied iodized poppy oil), and then embolization with a hemostatic tampon until the blood does not flow so far. The results showed that from the first chemical embolization, the total median survival of 10 months. When the degree of cirrhosis was classified according to Child-Pugh, the median survival time of grade A and grade B was higher than those with extrahepatic metastasis (P <0. 02), which were 14 months and 3 months respectively. There was a significant difference in the median survival of metastatic carcinomas with fewer vessels than those with fewer vessels (P <0.01). The most common side effects were transient fever, abdominal pain and fatigue. There were 3 People die. Schistosomiasis of liver metastasis of colorectal cancer with poor efficacy of chemotherapy, and more side effects, selective chemoembolization is not only effective and less side effects, can prevent liver failure and prolong survival