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目的观察自体角膜缘干细胞移植术治疗翼状胬肉的临床效果。方法翼状胬肉11例12只眼,采用手术显微镜下切除局部病灶,然后行自体角膜缘干细胞移植术,术后随访6~15个月(平均11个月)。结果术后角膜上皮愈合良好,无排斥反应或其他并发症发生。随访期间1只眼复发,复发率为8.3%。结论应用自体角膜缘干细胞移植术为受损的角膜缘提供新的健康干细胞,可有效地防止翼状胬肉复发,起到美容的效果。
Objective To observe the clinical effect of autologous limbal stem cell transplantation in the treatment of pterygium. Methods 11 cases of pterygium in 12 eyes underwent surgical resection of the local lesion, and then autologous limbal stem cell transplantation, followed up for 6 to 15 months (mean 11 months). Results The corneal epithelium healed well without rejection or other complications. One eye had a recurrence during follow-up, with a recurrence rate of 8.3%. Conclusion Autologous corneal limbal stem cell transplantation provides a new healthy stem cell for damaged corneal limbs, which can effectively prevent the recurrence of pterygium and have a cosmetic effect.