We experimentally investigate the frequency response of near-wall coherent structures to localized periodic blowing and suction through a spanwise slot in a turbulent boundary layer by changing the frequency of periodic disturbance at similar velocities of free stream.The effects of blowing and suction disturbance on energy redistribution,turbulent intensity u+rms over y+ and waveforms of phase-averaged velocity during sweeping process are respectively discussed under three frequencies of periodic blowing and suction in near-wall region of turbulent boundary layer,compared with those in a standard turbulent boundary layer.The most effective disturbancefrequency is figured out in this system.