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目的探讨硝普钠联合垂体后叶素在支气管扩张咯血治疗中的疗效。方法收集2012年11月至2015年12月收治的支气管扩张咯血患者96例,根据治疗药物的不同随机分为对照组(应用垂体后叶素治疗)和观察组(应用硝普钠联合垂体后叶素治疗),对比两组肺动脉压、出血改善情况,评估疗效,记录不良反应。结果观察组治疗总有效率为89.58%,不良反应发生率为8.33%,均优于对照组,P均<0.05。治疗前,两组患者肺动脉压无明显差异,P>0.05。治疗后观察组肺动脉压低于对照组,出血时间及出血量亦均少于对照组(P<0.05)。结论硝普钠联合垂体后叶素治疗支气管扩张咯血疗效好,不良反应少,安全性高,值得应用。
Objective To investigate the curative effect of nitroprusside combined with pituitrin in the treatment of bronchiectasis and hemoptysis. Methods Ninety-six patients with bronchiectasis and hemoptysis admitted from November 2012 to December 2015 were randomly divided into control group (treated with pituitrin) and observation group (treated with sodium nitroprusside plus posterior pituitary Su-treatment), compared two groups of pulmonary arterial pressure, bleeding to improve the situation, assess the efficacy, record adverse reactions. Results The total effective rate of observation group was 89.58%, the incidence of adverse reactions was 8.33%, which were better than the control group, P <0.05. Before treatment, there was no significant difference in pulmonary arterial pressure between the two groups (P> 0.05). After treatment, pulmonary arterial pressure in the observation group was lower than that in the control group, bleeding time and bleeding volume were also less than the control group (P <0.05). Conclusion Sodium nitroprusside combined with pituitrin treatment of bronchiectasis hemoptysis effective, less adverse reactions, high safety, it is worth to apply.