我们自1974年10月至1975年8月试用国产抗结核新药利福平治疗矽肺结核住院患者10例。现将初步结果报告如下。临床资料一般情况:患者均为男性,平均年龄47岁(最大年龄56岁,最小年龄42岁)。均为北京矿务局井下粉尘作业工人。经北京矿务局1963、1964年普查确诊为矽肺。矽肺分期按治疗前胸部平片,其中Ⅰ期1例、Ⅱ期8例、Ⅲ期1例。结核病变:均为大片浸润型肺结核,并有空洞形成,经一、二线抗痨药物治疗无效, From October 1974 to August 1975, we piloted a trial of 10 domestic in-patients with silicotuberculosis in domestic anti-tuberculosis drug rifampicin. The preliminary results are reported below. General clinical data: All patients were male, with an average age of 47 years (maximum age 56 years, minimum age 42 years). All are miners dusting workers in Beijing Mining Bureau. The Beijing Mining Bureau 1963, 1964 census diagnosed as silicosis. Silicosis staging by chest film before treatment, of which 1 case of stage Ⅰ, 8 cases of stage Ⅱ, 1 case of stage Ⅲ. Tuberculosis: are large infiltrative pulmonary tuberculosis, and there are empty formation, the first and second-line anti-tuberculosis drugs ineffective treatment,