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目的分析莱芜市某钢铁企业工人乙型肝炎病毒学检测情况,并对HBsAg感染情况及ALT进行相关性研究。方法采用酶联免疫吸附试验ELISA和速率法进行HBsAg和ALT的检测。结果 3 968名工人HBsAg阳性率为0.98%,不同性别和不同年龄组的HBsAg阳性率比较差别均有统计学意义(P<0.05),不同年龄组HBsAg阳性者的ALT异常率差别无统计学意义(P>0.05)。结论莱芜市某钢铁企业工人HBsAg阳性率显著低于全国平均水平,乙肝疫苗接种及健康教育起着重要作用。
Objective To analyze the status of hepatitis B virus (HBV) detection in workers in an iron and steel enterprise in Laiwu City and to study the correlation between HBsAg infection and ALT. Methods The detection of HBsAg and ALT by enzyme-linked immunosorbent assay (ELISA) and rate assay. Results The positive rate of HBsAg in 3 968 workers was 0.98%. The positive rates of HBsAg in different sexes and different age groups were significantly different (P <0.05). There was no significant difference in ALT abnormalities among HBsAg positive patients of different age groups (P> 0.05). Conclusions The positive rate of HBsAg in workers in an iron and steel enterprise in Laiwu City is significantly lower than the national average. Hepatitis B vaccination and health education play an important role.