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目的探讨老年2型糖尿病并发周围神经病变的危险因素。方法将290例老年2型糖尿病按是否并发周围神经病变分为DPN组和NDPN组,检查血脂、空腹血糖、空腹胰岛素,计算胰岛素抵抗指数(HOMA-IR),比较各项指标。结果 DPN组与NDPN组病程、年龄比较有差异(P<0.05);FBG、FINS、TC、TG、HOMA-IR比较有差异(P<0.05)。结论糖尿病的年龄、病程、胰岛素抵抗、脂代谢紊乱、高血糖参与DPN的发生、发展、遗传因素、高血脂症、肥胖和年龄增加(老年)等均可导致神经操作的危险因素。
Objective To investigate the risk factors of peripheral neuropathy in elderly type 2 diabetic patients. Methods 290 cases of type 2 diabetes mellitus were divided into DPN group and NDPN group according to whether they had peripheral neuropathy or not. Blood lipids, fasting blood glucose and fasting insulin were measured, and insulin resistance index (HOMA-IR) was calculated. All the indexes were compared. Results The course and age of DPN group and NDPN group were significantly different (P <0.05). FBG, FINS, TC, TG and HOMA-IR were significantly different (P <0.05). Conclusion The age, duration of diabetes, insulin resistance, dyslipidemia, hyperglycemia involved in the occurrence and development of DPN, genetic factors, hyperlipidemia, obesity and increased age (elderly) all lead to risk factors for nerve manipulation.