分析１１４例确诊的慢性淋巴细胞性甲状腺炎。本病多数具有甲状腺肿大或呈结节变，质硬，易伴发甲减。甲状腺球蛋白抗体（ＴＧＡ），甲状腺微粒体抗体（ＭＣＡ）阳性率增高，作者对本病的诊断进行探讨，认为１．凡ＴＧＡ、ＭＣＡ阳性者具有下列二项之一即可诊断，（１）甲状腺肿大或星结节变，质地中至硬；（２）甲状腺功能减退。２ＴＧＡ、ＭＣＡ阴性者有甲状腺肿大，质硬或呈结节变怀疑本病时应作ＦＮＡＢ（甲状腺针吸细胞学检查）以明确诊断。 114 cases of diagnosed chronic lymphocytic thyroiditis were analyzed. Most of the disease with goiter or nodular change, hard, easy with hypothyroidism. Thyroglobulin antibody (TGA), thyroid microsomal antibody (MCA) positive rate increased, the author of the diagnosis of the disease are discussed, that 1. Where TGA, MCA-positive who have one of the following two can be diagnosed, (1) goiter or astroglia, texture to hard; (2) hypothyroidism. 2TGA, MCA-negative were goiter, hard or nodular change should suspect the disease when the FNAB (thyroid needle aspiration cytology) to confirm the diagnosis.