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目的分析研讨免疫组织化学检测在乳腺病理疾病中的临床诊断作用。方法分组研讨88例患者(乳腺疾病患者),88例患者均来自本院2014年5月至2016年4月期间收治的乳腺病患者,44例对照组(常规检查)和44例研究组(免疫组织化学检测),观察其临床检查状况,并对比。结果对比对照组和研究组乳腺病疾病判定中,免疫组织化学检测比常规性检测更具有优势性(P<0.05);乳腺良性增生与正常乳腺组织均存在MEC,排除腺性腺病。大部分乳腺恶性疾病者均缺乏MEC。所以,临床诊断区分恶性肿瘤、良性乳腺疾病的一个主要依据为判定有无MEC。乳腺组织正常HE切面之上,识别MEC的难度较低,但因大部分良性乳腺疾病均可让乳腺细胞小叶和成分结构发生变化,在辨识MEC上加大了难度。结论临床检查诊断乳腺疾病,可考虑给予免疫组织化学检测方式,其诊断价值高,应用性和推广性均较大。
Objective To investigate the clinical diagnostic role of immunohistochemical detection in breast pathological diseases. Methods A total of 88 patients (breast disease patients) were enrolled in this study. 88 patients were recruited from our hospital from May 2014 to April 2016 for breast disease, 44 patients in the control group (routine examination) and 44 patients in the study group Histochemical test), observe the clinical examination of the situation, and contrast. Results Compared with the control group and the study group, immunohistochemistry was more effective than the routine test (P <0.05). In the benign hyperplasia of mammary gland and normal breast tissues, MEC was found and adenocarcinoma was excluded. Most patients with malignant breast disease lack MEC. Therefore, the clinical diagnosis of malignant tumors, one of the main basis for the diagnosis of benign breast disease to determine whether the MEC. Above the normal HE section of breast tissue, the difficulty of recognizing MEC is low, but because most benign breast diseases can change the structure of breast cells and leaflets, it is more difficult to identify MECs. Conclusion Clinical diagnosis of breast disease can be considered given immunohistochemical detection of high diagnostic value, applicability and promotion of large.