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目的:探讨子宫肌瘤的发生与雌、孕激素的关系。方法:应用 SP免疫组化方法测定45例子宫肌瘤瘤体和非瘤肌组织的雌、孕激素受体含量。结果:子宫肌瘤雌激素受体阳性率为66.67%,孕激素受体阳性率为57.78%,非瘤肌组织雌激素受体阳性率为46.67%,孕激素受体阳性率为28.89%,两组间差异有显著性(P<0. 05)。结论:子宫肌瘤雌、孕激素受体含量比激素水平更能确切反映激素的作用,子宫肌瘤的发病并非因血雌、孕激素水平的升高直接引起,而可能与雌、孕激素受体的升高有关。
Objective: To investigate the relationship between the occurrence of uterine fibroids and estrogen and progesterone. Methods: SP immunohistochemistry was used to determine the levels of estrogen and progesterone receptors in 45 cases of uterine leiomyomas and non-tumor muscle tissues. Results: The positive rate of estrogen receptor in uterine fibroids was 66.67%, the positive rate of progesterone receptor was 57.78%, the positive rate of non-tumor muscle estrogen receptor was 46.67%, positive of progesterone receptors. The rate was 28.89%. There was a significant difference between the two groups (P<0.05). Conclusion: The levels of estrogen and progesterone receptors in uterine fibroids can better reflect the effect of hormones than hormone levels. The incidence of uterine fibroids is not directly caused by the increase of blood estrogen and progesterone levels, but may be related to estrogen and progesterone hormones. The height of the body is related.