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99％纯度的敌锈钠,以不同剂量给小鼠灌胃,其LD_(50)>5,000mg/kg。在亚急性毒性实验中,实验动物组的白细胞总数和血清谷丙转氨酶均较对照组有明显升高。统计学有显著性差异(P<0.05)。同时还观察到各给药组小鼠肝体积增大,胞浆疏松、病变广泛;而对照组动物未见异常。此外,还对两种动物进行尿液检查和致畸胎实验,均无明显变化,实验结果表明敌锈钠属低毒性农药。
99% purity of the enemy sodium rust, mice were given different doses of gavage, the LD_ (50)> 5,000mg / kg. In subacute toxicity experiments, the total number of leukocytes and serum alanine aminotransferase in experimental animals were significantly higher than those in control group. There was a statistically significant difference (P <0.05). At the same time, it was also observed that the liver volume of each administration group was increased, the cytoplasm was loose and the lesions were extensive; while the animals in the control group showed no abnormalities. In addition, urine tests and teratogenicity tests were conducted on both animals without significant changes. The experimental results show that the enemy rust sodium is a low toxic pesticide.