过敏性紫癜是一种毛细血管变态反应性出血性疾病,以广泛的小血管炎症为病理基础,以皮肤紫癜、消化道黏膜出血、关节肿痛、腹痛、便血和血尿的症状为主要临床表现[1,2]。过敏性紫癜各年龄段均可发病,以学龄儿童最多见,3~14岁为好发年龄[3]。当肾脏受累时称为紫癜性肾炎,严重时可表现为肾病综合征[4],过敏性紫癜肾脏受累发生率20%~80%[5]。治疗方案及药物的选择直接影响患儿的预后[6]。过敏性 Henoch-Schonlein purpura is a capillary hemorrhagic allergic disease with a wide range of small blood vessel inflammation as the pathological basis of the skin purpura, gastrointestinal mucosal hemorrhage, joint swelling and pain, abdominal pain, blood in the stool and hematuria as the main clinical manifestations [ 1,2]. Henoch-Schonlein purpura can occur in all age groups, the most common in school-age children, 3 to 14 years of age as a good age [3]. When the kidneys involved when called purpura nephritis, severe nephrotic syndrome can be manifested [4], allergic purpura, the incidence of renal involvement 20% to 80% [5]. Treatment options and drug choice directly affect the prognosis of children [6]. Allergic