妊娠合并外阴阴道假丝酵母菌感染对母婴结局的影响

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目的分析妊娠合并外阴阴道假丝酵母菌感染对母婴结局的影响。方法选择上海市松江区泗泾医院2011年2月-2012年1月定期产前检查的妊娠者157例作为研究对象,均有完整的产检及生产资料,其中妊娠合并外阴阴道假丝酵母菌感染者54例作为观察组,其余103例作为正常对照组,比较两组的母婴结局。结果观察组的妊娠并发症发生率为14.8%,明显高于对照组的2.9%(P<0.05);观察组的剖宫产率为37.0%,明显高于对照组的21.4%(P<0.05);观察组新生儿早产率明显高于对照组(P<0.05),但两组新生儿的阿氏评分比较差异无统计学意义(P>0.05);观察组新生儿尿布皮炎及鹅口疮发生率分别为11.1%、9.3%,均明显高于对照组的1.9%、1.0%(P均<0.05)。结论妊娠合并外阴阴道假丝酵母菌感染会增加妊娠期并发症以及新生儿感染的发生,对母婴结局有不利影响,临床上应通过产检及早发现感染,并及时采取正确的处理措施以改善母婴预后。 Objective To analyze the influence of pregnancy with vulvovaginal Candida infection on maternal and infant outcomes. Methods 157 pregnant women with regular prenatal examination in Sijing Hospital of Songjiang District of Shanghai from February 2011 to January 2012 were selected as study subjects. All of them had complete examination and means of production, of which pregnant women with vulvovaginal Candida infection 54 cases as the observation group, and the remaining 103 cases as a normal control group, maternal and infant outcomes were compared between the two groups. Results The incidence of pregnancy complications in the observation group was 14.8%, significantly higher than that in the control group (2.9%, P <0.05). The rate of cesarean section in the observation group was 37.0%, significantly higher than that in the control group (21.4%, P 0.05 ). The neonatal preterm birth rate in the observation group was significantly higher than that in the control group (P <0.05), but there was no significant difference between the two groups (P> 0.05). Neonatal dermatitis and thrush occurrence Rates were 11.1% and 9.3%, respectively, which were significantly higher than those in the control group (1.9% and 1.0%, P <0.05). Conclusion Pregnancy complicated with vulvovaginal Candida infection will increase the incidence of complications during pregnancy and neonatal infection, which may have an adverse effect on maternal and infant outcomes. Clinically, infection should be detected early by clinical examination and the correct treatment should be taken in time to improve the mother Baby prognosis.
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