神经肿瘤的分子遗传学研究揭示了DNA的变化,包括再排列、缺失、放大和基因组序列的突变。两种人类疾病,成视网膜细胞瘤和双侧听神经纤维瘤(BANF)的研究表明分予遗传学方法有助于理解神经肿瘤形成的机制。成视网膜细胞瘤是幼年期一种罕见的恶性肿瘤。虽然大多数病例是偶尔发生的和单侧的,但大约15％的病例是遗传的和双侧的。成视网 Molecular genetic studies of neuronal tumors reveal changes in DNA, including rearrangements, deletions, amplifications, and mutations in genomic sequences. Studies of two human diseases, retinoblastoma and bilateral auditory neurofibromatosis (BANF), have shown that the classification of genetic methods helps to understand the mechanisms underlying neuronal tumor formation. Retinoblastoma is a rare malignancy in childhood. Although most cases are sporadic and unilateral, approximately 15% of cases are hereditary and bilateral. Chengshiwang