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目的：观察丹参多酚酸盐在治疗冠心病、心绞痛患者的临床疗效。方法在常规冠心病二级预防，心绞痛发作需要硝酸酯类药物（舌下含服或缓慢静滴）缓解基础上，予以5％葡萄糖注射液250ml＋丹参多酚酸盐200mg静滴，共2周，观察患者心绞痛、心电图、血沉、需要硝酸酯类药物次数等指标变化。结果二组比较，观察组患者心绞痛缓解显效及总有效率明显高于对照组，且 P＜0．05，观察组患者心电图改善总有效率明显高于对照组，且 P＜0．05，观察组完全停用硝酸酯类药物明显高于对照组，且 P＜0．05，观察组硝酸酯类药物用量不变情况明显低于对照组，观察组血沉变化明显高于对照组，且 P＜0．05，差异具有统计学意义。结论丹参多酚酸盐在治疗冠心病、心绞痛患者发挥重要作用，尤其在基层医院，无急诊冠状动脉造影及支架植入术等积极手段情况下，值得进一步推广及应用。“,”Objective To observe the clinical effect of salvianolate in the treatment of patients with coronary heart disease ,angina pectoris .Methods In the basis of two grade prevention of coronary heart disease and angina pectoris need nitrates (sublingual or slow intravenous drip) to alleviate ,the patients were given 5%Glucose Injection 250ml+ salvianolate intravenous infusion of 200mg for 2 weeks ,then observed the chan-ges in patients with angina pectoris ,electrocardiogram ,blood sedimentation ,need to change the number of nitrates index .Results The angina effect and the total effective rate ,ECG improvement in the treatment group were significantly higher than the control group ( P<0 .05) .Patients in the treatment group who completely discontinued nitrates were significantly higher than the control group ( P<0 .05) .The nitrates amount of the treatment group was significantly lower than the control group ,but whose ESR was signifi-cantly higher than the control group( P<0 .05) .Conclusion Salvianolate plays an important role in the treatment of patients with coronary heart disease and angina pectoris .It is worthy of further promotion and application ,especially at the basic level hospital which no emergency coronary angiography and stent im-plantation under positive means .