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DNA作为细胞的基因物质传递遗传特性,控制生命的一切活动。但人们迄今对真核细胞基因的特异性表达的机制还难以解释。最近,苏联科学院分子生物学研究所Se-verin和同事所进行的工作使我们对cAMP在真核细胞基因表达调控方面的作用有了新的了解。有人根据大量的实验资料,提出了蛋白磷酸化调控基因表达的模型。本文就近年来在cAMP调控基因表达这方面所取得的进展做一简略的综述。最近,有人在培养的动物细胞中加入
DNA as a genetic material for the transmission of genetic characteristics of the cell, control all activities of life. However, the mechanism by which human eukaryotic cell genes have been specifically expressed so far is difficult to explain. Recently, the work of Se-verin and colleagues at the Institute of Molecular Biology at the Soviet Academy of Sciences has given us a new understanding of the role of cAMP in the regulation of eukaryotic gene expression. Some people based on a large number of experimental data, put forward a model of protein phosphorylation regulation of gene expression. This article in recent years in cAMP regulation of gene expression in this area made a brief overview of the progress made. Recently, it was added to cultured animal cells