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应用ＡＢＣ免疫组织化学技术测定正常喉、良性病变和喉癌的雌激素受体。喉癌细胞阳性率与对照组间的差异无显著性。正常上皮阳性反应的着色部位为基底细胞、棘细胞及颗粒细胞，而病变组织相当于基底细胞处为阴性。不同分化程度喉癌雌激素受体阳性率之间。雌激素受体阳性和用性病例生存率之间的差异有显著性。雌激素受体的测定有助于良恶性的鉴别诊断和喉癌患者的预后判定，对指导内分泌治疗可能有意义。
ABC immunohistochemistry was used to determine the estrogen receptor in normal laryngeal, benign lesions and laryngeal cancer. There was no significant difference between the positive rate of laryngeal cancer cells and the control group. The normal epithelial positive staining sites for the basal cells, spine cells and granulosa cells, while the lesion is equivalent to basal cells at the negative. Differentiation of laryngeal estrogen receptor between the positive rate. There was a significant difference between the estrogen receptor positive and the use case survival rates. Determination of estrogen receptor contribute to the differential diagnosis of benign and malignant and prognosis of laryngeal cancer patients may guide the endocrine therapy may be meaningful.