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目的探讨外源性呼气末正压（PEEP）对气过压力影响的规律。方法通过模拟肺（静态顺应性为28ml／cmH2O,气道阻力为0．8cmH2O·L－1·S-1）试验，设置不同的PEEP，观察气道压力（修压、平均压、平台压）的变化。结果外源性PEEP从0增加至3cmH2O时，气过压力增幅最大，平均每增加1cmH2OPEEP，气道峰压、平台压增加3．5～4．1cmH2O,当PEEP增加至12cmH2O时，气道峰压和平台压增加了20cmH2O以上。结论外源性PEEP对气造压力的影响，可产生一种“扩大”效应，这种“扩大”效应在低水平的PEEP时尤为显著。在使用人工机械通气时，如需设置外源性PEEP时，必须严密监测气道压力的变化，以防止肺损伤。
Objective To investigate the influence of exogenous positive end expiratory pressure (PEEP) on gas overpressure. Methods Different PEEPs were set up to simulate the pulmonary (static compliance of 28ml / cmH2O and airway resistance of 0.8cmH2O · L-1 · S-1). Airway pressure (pressure, average pressure and plateau pressure) The change. Results When the exogenous PEEP increased from 0 to 3 cmH2O, the increase of air pressure was the largest, with an average increase of 1 cmH2OPEEP and peak airway pressure, and the plateau pressure increased 3.5-4.1 cmH2O. When the PEEP increased to 12 cmH2O, peak airway pressure And platform pressure increased by more than 20cmH2O. Conclusion The effect of exogenous PEEP on gas pressure can produce an “enlarging” effect, which is especially noticeable at low levels of PEEP. In the use of artificial ventilation, if you need to set exogenous PEEP, you must closely monitor changes in airway pressure to prevent lung injury.