随着社会老龄化以及病毒性肝炎等其他肝病的控制,与肥胖和代谢综合征相关脂肪性肝病已经成为严重的健康问题。目前认为,脂肪肝疾病谱包括单纯脂肪肝、脂肪性肝炎及其相关肝硬化,甚至肝细胞癌。在上述脂肪肝进展过程中,影响因素很多,例如,年龄、内脏性肥胖、基因缺陷、胰岛素抵? With the social aging and control of other liver diseases such as viral hepatitis, fatty liver disease associated with obesity and metabolic syndrome has become a serious health problem. At present, the spectrum of fatty liver diseases includes simple fatty liver, steatohepatitis and their associated cirrhosis and even hepatocellular carcinoma. In the process of fatty liver progress, many factors, such as age, visceral obesity, genetic defects, insulin resistance?