目的:观察气管内注入立止血加机械通气治疗新生儿肺出血的临床疗效。方法:对2005年1月～2012年4月治疗的56例新生儿肺出血患儿在呼吸机等综合治疗的基础上气管内注入立止血,观察其治疗效果及并发症。结果:53例新生儿肺出血患儿中存活50例(94.3%),肺出血停止时间(5.7±2.4)h,呼吸机使用时间(36.1±15.1)h。未经机械通气治疗的3例患儿均死亡。结论:机械通气联合气管内注入立止血治疗新生儿肺出血效果显著。 Objective: To observe the clinical effect of tracheal injection of hemostatic plus mechanical ventilation in the treatment of neonatal pulmonary hemorrhage. Methods: Fifty-six neonates with pulmonary hemorrhage treated from January 2005 to April 2012 were infused with hemostatic blood through the endotracheal tube on the basis of comprehensive treatment such as ventilator. The curative effect and complications were observed. Results: The survival of 53 newborns with pulmonary hemorrhage in 50 cases (94.3%), pulmonary bleeding stopped (5.7 ± 2.4) h, ventilator use time (36.1 ± 15.1) h. All 3 children without mechanical ventilation died. Conclusion: Mechanical ventilation combined with intra-tracheal injection of anti-hemostatic effect of neonatal pulmonary hemorrhage was significant.