目的:探讨高危儿早期干预方法的可行性及有效性。方法:将2010年1月～2010年12月在连云港市妇幼保健院自愿接受调查的374例高危儿按照父母依从性分为干预163例和对照Ⅰ组211例,同时选取150例同期出生的正常足月儿为对照Ⅱ组。干预组自出院后按照鲍秀兰教授0～3岁早期教育大纲进行以家庭干预为主、定期到医院随诊方式进行干预;对照Ⅰ组及对照Ⅱ组按国家0～6岁儿童健康管理服务规范要求进行定期体检。3组研究对象均在周岁时测量身长和体重,并用Gesell婴幼儿发育诊断量表检测其发育商。结果:1周岁时,3组研究对象之间的身长和体重比较差异无统计学意义(P>0.05);动作能区和应人能区的发育商对照,Ⅱ组>干预组>对照Ⅰ组;其他能区发育商及平均发育商比较,干预组高于对照Ⅰ组(P<0.05),而与对照Ⅱ组相比差异无统计学意义(P>0.05)。结论:对高危儿进行早期干预,可以促进高危儿神经行为发育和体格发育。 Objective: To explore the feasibility and effectiveness of early intervention in high-risk infants. Methods: From January 2010 to December 2010, 374 high risk infants voluntarily under investigation in Lianyungang MCH were divided into intervention group (n = 163) and control group (n = 211). At the same time, 150 normal subjects Full-term children for the control group Ⅱ. In the intervention group, they were mainly intervened by family intervention according to Professor Bao Xiu-lan’s early education program of 0 ~ 3 years old after hospital discharge, and they were intervened regularly to the hospital. The control group Ⅰ and control group Ⅱ according to the national health management service standard for children aged 0 ~ 6 years Regular physical examination. All three groups were surveyed for body length and weight at the age of 4 and their developmental firm was tested using the Gesell Infant Developmental Diagnostic Scale. Results: At 1 year of age, there was no significant difference in body length and weight between the three groups (P> 0.05) (P <0.05). Compared with control group Ⅱ, the difference was not statistically significant (P> 0.05). Conclusion: Early intervention in high-risk children can promote behavioral development and physical development of high-risk children.